SYT8

Across TCGA patient cohorts, SYT8 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,596 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SYT8-associated proteins across cancer lineages are LAMB3, PPL, and ANXA2. Each is linked with SYT8 in more than 5 cancer types. Because this analysis shows association rather than direction, both SYT8-to-partner and partner-to-SYT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT8 versus LAMB3 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT8→partner) and Y-score (partner→SYT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LAMB3 →	+0.952	+1.316	<.001	<.001	2	6
OV	PPL →	+1.063	+0.850	<.001	.002	3	5
UCEC	ANXA2 →	+0.622	+1.093	<.001	<.001	3	5
LSCC	IL18 →	+0.618	+0.966	<.001	<.001	3	4
BRCA	ITGB4 →	+0.626	+1.355	<.001	<.001	3	4
OV	KRT19 →	+0.956	+0.864	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,596 associations by consensus.

SYT8 vs LAMB3 — LSCC

Explore this scatter interactively →