SYT8

Across TCGA patient cohorts, SYT8 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYT8-associated genes across cancer lineages are Basophils, CD8+ Tcm, and Melanocytes. Each is linked with SYT8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT8-to-partner and partner-to-SYT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by SYT8-low versus SYT8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT8→partner) and Y-score (partner→SYT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Basophils →	+0.149	+1.893	.034	.031	3	1
UCEC	CD8+ Tcm →	+0.032	+2.935	.004	.013	3	1
UCEC	Melanocytes →	+0.013	+3.053	.040	.018	1	2

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Basophils by SYT8 expression — SKCM

Explore this box plot interactively →