SYT7

Across TCGA cell cohorts, SYT7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,832 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SYT7-associated GO terms across cancer lineages are Establishment or maintenance of epithelial cell apical/basal polarity, Positive regulation of regulated secretory pathway, and Regulation of protein localization to nucleus. Each is linked with SYT7 in more than 8 cancer types. Because this analysis shows association rather than direction, both SYT7-to-partner and partner-to-SYT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of epithelial cell apical/basal polarity grouped by SYT7-low versus SYT7-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT7→partner) and Y-score (partner→SYT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Establishment or maintenance of epithelial cell apical/basal polarity →	+0.108	+1.297	<.001	<.001	3	9
BREAST	Positive regulation of regulated secretory pathway →	+0.104	+2.711	<.001	<.001	3	9
STOMACH	Regulation of protein localization to nucleus →	+0.098	+2.721	<.001	<.001	3	8
STOMACH	Protein localization to perinuclear region of cytoplasm →	+0.134	+2.321	.001	.002	3	8
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.154	+2.688	<.001	<.001	3	8
PANCREAS	Positive regulation of Rho protein signal transduction →	+0.093	+1.403	.004	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

Establishment or maintenance of epithelial cell apical/basal polarity by SYT7 expression — LIVER

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