SYT4

Across TCGA patient cohorts, SYT4 protein abundance is significantly associated with the RNA expression of many other genes, with 326 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT4-associated genes across cancer lineages are ABHD4, TANGO6, and TAF1C. Each is linked with SYT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT4-to-partner and partner-to-SYT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT4 versus ABHD4 in GBM, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT4→partner) and Y-score (partner→SYT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ABHD4 →	-0.503	-0.547	<.001	<.001	3	1
GBM	TANGO6 →	-0.254	-0.348	.007	.006	3	1
GBM	TAF1C →	-0.371	-0.387	.002	.002	3	1
GBM	USP10 →	-0.294	-0.492	.004	.001	3	1
GBM	MTHFSD →	-0.346	-0.504	.001	.002	3	1
GBM	ZNF174 →	-0.308	-0.594	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 326 associations by consensus.

SYT4 vs ABHD4 — GBM

Explore this scatter interactively →