SYT4

Across TCGA cell cohorts, SYT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,553 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYT4-associated GO terms across cancer lineages are Negative regulation of cell-cell adhesion, 5S class rRNA transcription by RNA polymerase III, and Regulation of chromatin organization. Each is linked with SYT4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SYT4-to-partner and partner-to-SYT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell-cell adhesion grouped by SYT4-low versus SYT4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT4→partner) and Y-score (partner→SYT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cell-cell adhesion →	-0.076	-2.226	<.001	.002	3	5
BONE	5S class rRNA transcription by RNA polymerase III →	+0.146	+1.690	<.001	.008	2	6
LARGE_INTESTINE	Regulation of chromatin organization →	+0.052	+0.061	.002	<.001	2	5
BONE	Intracellular copper ion homeostasis →	-0.122	-1.893	<.001	<.001	3	4
SOFT_TISSUE	Regulation of sodium ion transmembrane transport →	-0.127	-0.328	<.001	.005	3	4
SOFT_TISSUE	Regulation of protein maturation →	-0.166	-0.234	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,553 associations by consensus.

Negative regulation of cell-cell adhesion by SYT4 expression — BONE

Explore this box plot interactively →