SYT12

Across TCGA patient cohorts, SYT12 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SYT12-associated GO terms across cancer lineages are Endodermal cell differentiation, Cell differentiation involved in embryonic placenta development, and Negative regulation of phospholipid metabolic process. Each is linked with SYT12 in more than 20 cancer types. Because this analysis shows association rather than direction, both SYT12-to-partner and partner-to-SYT12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endodermal cell differentiation grouped by SYT12-low versus SYT12-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT12→partner) and Y-score (partner→SYT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Endodermal cell differentiation →	+0.075	+0.950	<.001	<.001	3	21
PAAD	Cell differentiation involved in embryonic placenta development →	+0.049	+1.129	<.001	<.001	3	19
THYM	Negative regulation of phospholipid metabolic process →	+0.074	+0.465	<.001	<.001	3	19
CHOL	Positive regulation by host of viral process →	+0.048	+2.494	.006	.007	1	20
PAAD	Endoderm formation →	+0.062	+0.968	<.001	<.001	3	18
STAD	Placenta development →	+0.042	+0.263	<.001	.004	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Endodermal cell differentiation by SYT12 expression — PAAD

Explore this box plot interactively →