SYPL1

Across TCGA patient cohorts, SYPL1 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,628 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SYPL1-associated proteins across cancer lineages are ARMC10, ATP1A1, and LPCAT3. Each is linked with SYPL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SYPL1-to-partner and partner-to-SYPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYPL1 versus ARMC10 in OV, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYPL1→partner) and Y-score (partner→SYPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARMC10 →	+0.483	+0.643	<.001	<.001	3	8
UCEC	ATP1A1 →	+0.893	+0.440	<.001	<.001	3	7
UCEC	LPCAT3 →	+0.952	+0.458	<.001	<.001	3	7
UCEC	SLC25A13 →	+0.494	+0.321	<.001	<.001	3	7
COAD	CEP170 →	-0.293	-0.275	.001	<.001	3	6
CCRCC	LMTK2 →	+0.394	+0.315	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,628 associations by consensus.

SYPL1 vs ARMC10 — OV

Explore this scatter interactively →