SYP-AS1

Across TCGA pan-cancer cohorts, SYP-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SYP-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SYP-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SYP-AS1 is over-expressed in tumor.

KIRC, COAD, and LIHC are the cancer types where SYP-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SYP-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.045	.035	3	view →
COAD	Female	All	+0.116	.032	2	view →
LIHC	All	All	+0.025	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SYP-AS1–KIRC

Open the KIRC breakdown →