SYNPO2L

Across TCGA patient cohorts, SYNPO2L RNA expression is significantly associated with the protein abundance of many other proteins, with 14,280 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SYNPO2L-associated proteins across cancer lineages are SH2D4A, PI16, and PRKG1_T517. Each is linked with SYNPO2L in more than 4 cancer types. Because this analysis shows association rather than direction, both SYNPO2L-to-partner and partner-to-SYNPO2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNPO2L versus SH2D4A in UCEC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNPO2L→partner) and Y-score (partner→SYNPO2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SH2D4A →	-0.589	-0.692	<.001	.004	3	5
GBM	PI16 →	+0.877	+0.514	.001	<.001	3	4
CCRCC	PRKG1_T517 →	+1.645	+0.235	<.001	<.001	3	4
CCRCC	SMOC2 →	+0.844	+0.101	<.001	<.001	3	4
HNSC	ARHGAP1 →	+0.301	+1.067	.004	<.001	3	4
CCRCC	VCAN_S2116 →	+1.157	+0.097	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,280 associations by consensus.

SYNPO2L vs SH2D4A — UCEC

Explore this scatter interactively →