SYNPO2L

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SYNPO2L RNA expression is significantly associated with the go_rna of many other GO terms, with 1,932 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SYNPO2L-associated GO terms across cancer lineages are Primary alcohol metabolic process, Protein modification by small protein removal, and ER overload response. Each is linked with SYNPO2L in more than 6 cancer types. Because this analysis shows association rather than direction, both SYNPO2L-to-partner and partner-to-SYNPO2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol metabolic process grouped by SYNPO2L-low versus SYNPO2L-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNPO2L→partner) and Y-score (partner→SYNPO2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEPrimary alcohol metabolic process →-0.075-1.393<.001<.00136
LIVERProtein modification by small protein removal →+0.037+0.184.006.00927
LIVERER overload response →+0.128+0.111<.001.00636
SOFT_TISSUEPhenol-containing compound metabolic process →-0.070-1.416<.001.00336
UPPER_AERODIGESTIVE_TRACTRegulation of macroautophagy →+0.039+0.173.008.00135
LARGE_INTESTINEDetection of light stimulus →-0.084-0.202.001.00635
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,932 associations by consensus.

Primary alcohol metabolic process by SYNPO2L expression — SOFT_TISSUE

Box plot of Primary alcohol metabolic process in SYNPO2L-low vs SYNPO2L-high samples in SOFT_TISSUE.

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Exploration