SYNPO2

Across TCGA cell cohorts, SYNPO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,696 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYNPO2-associated GO terms across cancer lineages are Endosomal transport, Golgi vesicle transport, and CD8-positive, alpha-beta T cell homeostasis. Each is linked with SYNPO2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SYNPO2-to-partner and partner-to-SYNPO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by SYNPO2-low versus SYNPO2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNPO2→partner) and Y-score (partner→SYNPO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endosomal transport →	+0.053	+1.044	<.001	.002	3	9
PANCREAS	Golgi vesicle transport →	+0.055	+0.292	.008	.009	3	9
PANCREAS	CD8-positive, alpha-beta T cell homeostasis →	+0.126	+0.270	<.001	<.001	3	9
PANCREAS	Proteasomal ubiquitin-independent protein catabolic process →	+0.100	+0.281	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.063	+0.921	<.001	.008	3	9
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+0.574	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,696 associations by consensus.

Endosomal transport by SYNPO2 expression — BONE

Explore this box plot interactively →