SYNM

Across TCGA cell cohorts, SYNM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,206 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYNM-associated GO terms across cancer lineages are Potassium ion transmembrane transport, Potassium ion transport, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with SYNM in more than 11 cancer types. Because this analysis shows association rather than direction, both SYNM-to-partner and partner-to-SYNM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transmembrane transport grouped by SYNM-low versus SYNM-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNM→partner) and Y-score (partner→SYNM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Potassium ion transmembrane transport →	-0.068	-2.225	.001	<.001	3	12
LUNG_NSCLC_LUSC	Potassium ion transport →	-0.072	-1.996	.002	.004	3	12
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.106	+1.370	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of telomerase RNA localization to Cajal body →	+0.072	+2.068	.002	.003	3	10
PANCREAS	Establishment of protein localization to organelle →	+0.043	+1.262	.001	.001	3	9
BLOOD_Lymphoma	Regulation of RNA splicing →	+0.059	+0.674	<.001	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,206 associations by consensus.

Potassium ion transmembrane transport by SYNM expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →