Across TCGA patient cohorts, SYNJ2BP mutation is significantly associated with the RNA expression of many other genes, with 795 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYNJ2BP-associated genes across cancer lineages are STOML2, TRUB2, and NDUFAF5. Each is linked with SYNJ2BP in more than 1 cancer types. Because this analysis shows association rather than direction, both SYNJ2BP-to-partner and partner-to-SYNJ2BP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNJ2BP→partner) and Y-score (partner→SYNJ2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STOML2 →	+0.635	+3.210	.001	.009	3	2
UCEC	TRUB2 →	+0.514	+3.374	.001	.004	3	2
UCEC	NDUFAF5 →	+0.430	+3.534	.003	.002	3	2
UCEC	PMS2P3 →	+0.583	+3.354	<.001	.005	3	2
UCEC	EMC8 →	+0.642	+3.502	<.001	.002	3	2
UCEC	RNA5SP205 →	+0.310	+3.267	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 795 associations by consensus.

Exploration

SYNJ2BP survival (RNA) · tumor vs normal (RNA) · all SYNJ2BP data types