Across TCGA patient cohorts, SYNJ2BP mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYNJ2BP-associated genes across cancer lineages are Ku80, MEK1, and VHL. Each is linked with SYNJ2BP in more than 1 cancer types. Because this analysis shows association rather than direction, both SYNJ2BP-to-partner and partner-to-SYNJ2BP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNJ2BP→partner) and Y-score (partner→SYNJ2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.324	+3.009	.008	.019	3	1
UCEC	MEK1 →	+0.469	+3.169	.014	.019	3	1
UCEC	VHL →	-0.964	-3.169	.006	.019	3	1
UCEC	Caspase-8 →	-0.304	-3.000	.020	.036	2	1
UCEC	EGFR_pY1068 →	-0.314	-3.321	.016	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SYNJ2BP survival (RNA) · tumor vs normal (RNA) · all SYNJ2BP data types