SYNJ2BP-COX16

Across TCGA patient cohorts, SYNJ2BP-COX16 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,153 significant associations in total. THYM shows the largest number of these associations.

The most reproducible SYNJ2BP-COX16-associated GO terms across cancer lineages are Protein desumoylation, Smoothened signaling pathway, and Cytoplasmic translational initiation. Each is linked with SYNJ2BP-COX16 in more than 25 cancer types. Because this analysis shows association rather than direction, both SYNJ2BP-COX16-to-partner and partner-to-SYNJ2BP-COX16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein desumoylation grouped by SYNJ2BP-COX16-low versus SYNJ2BP-COX16-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNJ2BP-COX16→partner) and Y-score (partner→SYNJ2BP-COX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Protein desumoylation →	+0.068	+0.315	<.001	.001	3	25
THYM	Smoothened signaling pathway →	+0.041	+0.391	<.001	<.001	3	24
LAML	Cytoplasmic translational initiation →	+0.065	+0.391	<.001	<.001	3	24
ACC	Positive regulation of transcription elongation by RNA polymerase II →	+0.037	+0.522	<.001	<.001	3	24
THYM	miRNA processing →	+0.047	+0.409	<.001	<.001	3	24
THYM	DNA alkylation repair →	+0.052	+0.312	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,153 associations by consensus.

Protein desumoylation by SYNJ2BP-COX16 expression — THYM

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