SYNJ1

Across TCGA patient cohorts, SYNJ1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,569 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYNJ1-associated genes across cancer lineages are PPP1R16B, LILRA1, and CEACAM4. Each is linked with SYNJ1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SYNJ1-to-partner and partner-to-SYNJ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNJ1 versus PPP1R16B in GBM, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNJ1→partner) and Y-score (partner→SYNJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R16B →	+1.722	+0.594	<.001	<.001	3	7
UCEC	LILRA1 →	+0.597	+0.258	<.001	<.001	3	6
LSCC	CEACAM4 →	+0.860	+0.217	<.001	<.001	3	6
HNSC	ARHGAP9 →	+0.966	+0.188	<.001	<.001	3	6
HNSC	PREX1 →	+0.700	+0.160	<.001	<.001	3	6
COAD	LILRB2 →	+0.966	+0.340	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,569 associations by consensus.

SYNJ1 vs PPP1R16B — GBM

Explore this scatter interactively →