SYNDIG1

Across TCGA cell cohorts, SYNDIG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 859 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SYNDIG1-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, Calcium ion transmembrane transport, and Regulation of pentose-phosphate shunt. Each is linked with SYNDIG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SYNDIG1-to-partner and partner-to-SYNDIG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alternative mRNA splicing, via spliceosome grouped by SYNDIG1-low versus SYNDIG1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNDIG1→partner) and Y-score (partner→SYNDIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Alternative mRNA splicing, via spliceosome →	+0.077	+0.555	<.001	.003	3	6
OVARY	Calcium ion transmembrane transport →	-0.046	-0.911	.001	.005	3	5
BLOOD_Myeloma	Regulation of pentose-phosphate shunt →	-0.083	-1.171	.001	.007	3	4
CNS	Regulation of stem cell population maintenance →	+0.047	+1.219	.002	.005	3	4
OVARY	Calcium ion transport →	-0.045	-0.864	.001	.009	3	4
KIDNEY	Mast cell activation →	-0.135	-1.018	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 859 associations by consensus.

Alternative mRNA splicing, via spliceosome by SYNDIG1 expression — OVARY

Explore this box plot interactively →