SYNDIG1

Across TCGA cell cohorts, SYNDIG1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,355 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SYNDIG1-associated genes across cancer lineages are RETREG2, ARG2, and WASHC2C. Each is linked with SYNDIG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYNDIG1-to-partner and partner-to-SYNDIG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNDIG1 versus RETREG2 in SKIN, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNDIG1→partner) and Y-score (partner→SYNDIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RETREG2 →	+0.761	+0.939	.001	.003	3	5
CNS	ARG2 →	-1.223	-0.858	.008	.004	3	5
SKIN	WASHC2C →	+0.759	+1.170	<.001	<.001	3	4
SKIN	SEPTIN4 →	+2.320	+0.991	<.001	<.001	3	4
BLOOD_Leukemia	TMCO4 →	+1.809	+0.728	.001	<.001	3	4
OVARY	HDAC11 →	+1.342	+0.966	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,355 associations by consensus.

SYNDIG1 vs RETREG2 — SKIN

Explore this scatter interactively →