SYCP2L

Across TCGA patient cohorts, SYCP2L mutation is significantly associated with the total protein of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYCP2L-associated genes across cancer lineages are FASN, PCNA, and ASNS. Each is linked with SYCP2L in more than 2 cancer types. Because this analysis shows association rather than direction, both SYCP2L-to-partner and partner-to-SYCP2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by SYCP2L-low versus SYCP2L-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCP2L→partner) and Y-score (partner→SYCP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FASN →	+0.413	+3.000	.009	.034	3	3
UCEC	PCNA →	+0.257	+1.938	<.001	.001	3	3
COAD	ASNS →	+0.754	+3.321	<.001	.009	3	3
UCEC	C-Raf →	+0.234	+2.643	<.001	<.001	3	3
COAD	PDCD4 →	-0.348	-1.991	.041	.031	3	3
UCEC	14-3-3_beta →	-0.100	-1.973	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

FASN by SYCP2L expression — COAD

Explore this box plot interactively →