SYCP2L

Across TCGA pan-cancer cohorts, SYCP2L RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SYCP2L data layer compared with 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SYCP2L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SYCP2L expression acts as an unfavorable survival marker, although some lineages such as ACC and SKCM show a favorable association.

UCEC, KICH, and ACC are the cancer types where SYCP2L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.545	0.841	<.001	62	view →
KICH	DFS	Median	III,IV	0.254	0.865	.002	45	view →
ACC	DFS	Quartile	All	0.572	0.195	.007	41	view →
KIRC	DFS	Tertile	All	0.410	0.685	.001	41	view →
SKCM	OS	Quartile	III,IV	0.860	0.686	.003	35	view →
HNSC	DFS	Median	IV	0.407	0.213	.001	31	view →
STAD	DFS	Median	IV	0.154	0.503	.008	27	view →
CESC	OS	Tertile	III,IV	0.613	0.848	.018	24	view →
THYM	DFS	Median	III,IV	1.000	0.456	.006	20	view →
LGG	OS	Quartile	All	0.834	0.662	<.001	20	view →
READ	OS	Quartile	All	0.907	0.499	.003	13	view →
SCLC	DFS	Median	IV	0.137	0.559	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SYCP2L–UCEC (OS)

Open the UCEC breakdown →