Across TCGA cell cohorts, SYCE1L mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SYCE1L-associated genes across cancer lineages are TNP1, ZP2, and KRTAP17-1. Each is linked with SYCE1L in more than 1 cancer types. Because this analysis shows association rather than direction, both SYCE1L-to-partner and partner-to-SYCE1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCE1L→partner) and Y-score (partner→SYCE1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.172	+5.415	<.001	.004	3	1
BLOOD_Leukemia	ZP2 →	+0.179	+4.409	<.001	.005	3	1
BLOOD_Leukemia	KRTAP17-1 →	+0.695	+5.060	.007	.001	3	1
BLOOD_Leukemia	TCP11X2 →	+0.151	+5.060	<.001	.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SYCE1L survival (RNA) · tumor vs normal (RNA) · all SYCE1L data types