SWAP70

Across TCGA patient cohorts, SWAP70 mutation is significantly associated with the RNA expression of many other genes, with 3,016 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SWAP70-associated genes across cancer lineages are RNU2-34P, RNU5E-10P, and OR11J5P. Each is linked with SWAP70 in more than 1 cancer types. Because this analysis shows association rather than direction, both SWAP70-to-partner and partner-to-SWAP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-34P grouped by SWAP70-low versus SWAP70-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SWAP70→partner) and Y-score (partner→SWAP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU2-34P →	+0.539	+5.303	<.001	.006	3	2
UCEC	RNU5E-10P →	+0.405	+1.821	.001	.001	3	2
UCEC	OR11J5P →	+0.010	+3.834	<.001	.007	3	2
SKCM	LINC02079 →	+0.141	+4.680	<.001	.007	3	2
UCEC	RPS10-NUDT3 →	+0.240	+1.724	<.001	.008	3	1
UCEC	DOC2B →	-1.023	-2.978	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,016 associations by consensus.

RNU2-34P by SWAP70 expression — HNSC

Explore this box plot interactively →