SVOP

Across TCGA patient cohorts, SVOP RNA expression is significantly associated with the protein abundance of many other proteins, with 13,447 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SVOP-associated proteins across cancer lineages are ZNF148_S412, ASRGL1, and ADD1. Each is linked with SVOP in more than 2 cancer types. Because this analysis shows association rather than direction, both SVOP-to-partner and partner-to-SVOP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SVOP versus ZNF148_S412 in COAD, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SVOP→partner) and Y-score (partner→SVOP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZNF148_S412 →	-0.589	-0.060	.001	.001	3	3
GBM	ASRGL1 →	+0.627	+1.329	<.001	<.001	3	3
GBM	ADD1 →	+0.429	+1.132	<.001	<.001	3	3
GBM	CHGB →	+1.292	+1.503	<.001	<.001	3	3
GBM	DDAH1 →	+0.455	+1.002	<.001	<.001	3	3
PDAC	DDOST →	-0.444	-0.424	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,447 associations by consensus.

SVOP vs ZNF148_S412 — COAD

Explore this scatter interactively →