Across TCGA patient cohorts, SVIP mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SVIP-associated genes across cancer lineages are CTHRC1P1, IGKV2-40, and RN7SL301P. Each is linked with SVIP in more than 1 cancer types. Because this analysis shows association rather than direction, both SVIP-to-partner and partner-to-SVIP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SVIP→partner) and Y-score (partner→SVIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CTHRC1P1 →	+0.256	+4.694	<.001	.007	3	1
UCEC	IGKV2-40 →	+0.925	+5.386	<.001	.001	3	1
UCEC	RN7SL301P →	+0.371	+4.809	<.001	.003	3	1
UCEC	MIR7151 →	+0.818	+4.484	<.001	.009	3	1
UCEC	LSP1P3 →	+0.669	+4.233	<.001	.009	3	1
COAD	RNA5SP509 →	+0.647	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

SVIP survival (RNA) · tumor vs normal (RNA) · all SVIP data types