SVEP1

Across TCGA cell cohorts, SVEP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,558 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SVEP1-associated GO terms across cancer lineages are Cytoplasmic translation, Positive regulation of translation, and Translational initiation. Each is linked with SVEP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SVEP1-to-partner and partner-to-SVEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by SVEP1-low versus SVEP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SVEP1→partner) and Y-score (partner→SVEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.099	+0.830	.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of translation →	+0.082	+0.847	<.001	<.001	3	9
BLOOD_Leukemia	Translational initiation →	+0.042	+0.206	.007	.003	3	9
BREAST	Response to type I interferon →	+0.122	+0.673	<.001	.002	3	9
CNS	Cellular response to type I interferon →	+0.082	+0.656	<.001	.008	3	9
UPPER_AERODIGESTIVE_TRACT	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.136	+0.679	.009	.006	1	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,558 associations by consensus.

Cytoplasmic translation by SVEP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →