SV2C

Across TCGA patient cohorts, SV2C RNA expression is significantly associated with the protein abundance of many other proteins, with 12,937 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SV2C-associated proteins across cancer lineages are RPL7, NDRG2, and DDX47. Each is linked with SV2C in more than 3 cancer types. Because this analysis shows association rather than direction, both SV2C-to-partner and partner-to-SV2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SV2C versus RPL7 in GBM, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SV2C→partner) and Y-score (partner→SV2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.358	-0.784	<.001	<.001	3	4
CCRCC	NDRG2 →	+0.425	+0.292	<.001	<.001	3	4
GBM	DDX47 →	-0.306	-1.151	<.001	<.001	3	4
GBM	IMPDH1 →	-0.377	-0.716	<.001	.002	3	4
GBM	MYO1E →	-0.274	-0.519	<.001	.004	3	3
GBM	PLBD1 →	-0.815	-0.727	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,937 associations by consensus.

SV2C vs RPL7 — GBM

Explore this scatter interactively →