SV2C

Across TCGA cell cohorts, SV2C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,086 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SV2C-associated GO terms across cancer lineages are Protein oxidation, Negative regulation of mRNA catabolic process, and Regulation of mRNA catabolic process. Each is linked with SV2C in more than 4 cancer types. Because this analysis shows association rather than direction, both SV2C-to-partner and partner-to-SV2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein oxidation grouped by SV2C-low versus SV2C-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SV2C→partner) and Y-score (partner→SV2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein oxidation →	-0.940	-0.682	<.001	.004	3	5
URINARY_TRACT	Negative regulation of mRNA catabolic process →	+0.082	+0.080	<.001	.008	3	5
LUNG_SCLC	Regulation of mRNA catabolic process →	+0.054	+0.838	<.001	.001	3	5
URINARY_TRACT	Regulation of inner ear receptor cell differentiation →	+0.645	+0.078	.008	.007	3	5
URINARY_TRACT	Regulation of mechanoreceptor differentiation →	+0.645	+0.078	.008	.007	3	5
OVARY	Negative regulation of mRNA metabolic process →	+0.056	+0.150	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,086 associations by consensus.

Protein oxidation by SV2C expression — LUNG_SCLC

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