SUV39H1

Across TCGA patient cohorts, SUV39H1 mutation is significantly associated with the RNA expression of many other genes, with 2,561 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUV39H1-associated genes across cancer lineages are RN7SKP196, USP9YP10, and RNU6-285P. Each is linked with SUV39H1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUV39H1-to-partner and partner-to-SUV39H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP196 grouped by SUV39H1-low versus SUV39H1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUV39H1→partner) and Y-score (partner→SUV39H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SKP196 →	+0.147	+5.906	<.001	.001	3	3
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	2
LUSC	RNU6-285P →	+0.509	+4.392	<.001	.006	3	2
LUSC	RN7SL456P →	+0.237	+5.578	<.001	.002	3	2
LUSC	RN7SL571P →	+0.365	+5.578	<.001	.002	3	2
LUSC	RPL39P28 →	+0.342	+4.652	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,561 associations by consensus.

RN7SKP196 by SUV39H1 expression — LUSC

Explore this box plot interactively →