SUSD3

Across TCGA patient cohorts, SUSD3 mutation is significantly associated with the RNA expression of many other genes, with 1,088 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUSD3-associated genes across cancer lineages are CHAF1A, ASMTL, and PLEKHH3. Each is linked with SUSD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUSD3-to-partner and partner-to-SUSD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAF1A grouped by SUSD3-low versus SUSD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD3→partner) and Y-score (partner→SUSD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHAF1A →	+0.691	+3.606	.002	.001	3	2
UCEC	ASMTL →	+0.586	+3.584	.002	.003	3	2
UCEC	PLEKHH3 →	+0.909	+3.595	<.001	.001	3	2
UCEC	PPP1R14B-AS1 →	+0.968	+3.584	<.001	.003	3	2
SKCM	DBIP2 →	+0.165	+2.978	<.001	.003	3	1
SKCM	MTCO1P49 →	+0.094	+2.788	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,088 associations by consensus.

CHAF1A by SUSD3 expression — UCEC

Explore this box plot interactively →