SUSD1

Across TCGA cell cohorts, SUSD1 mutation is significantly associated with the RNA expression of many other genes, with 281 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUSD1-associated genes across cancer lineages are DMRTB1, GNGT1, and OR2M3. Each is linked with SUSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUSD1-to-partner and partner-to-SUSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTB1 grouped by SUSD1-low versus SUSD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD1→partner) and Y-score (partner→SUSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
BLOOD_Leukemia	GNGT1 →	+0.076	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR2M3 →	+0.024	+4.409	<.001	.005	3	1
BLOOD_Leukemia	C20orf141 →	+0.225	+4.276	<.001	.007	3	1
LARGE_INTESTINE	GCAT →	+1.232	+3.212	.003	.006	3	1
LARGE_INTESTINE	CBY1 →	+0.742	+3.160	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 281 associations by consensus.

DMRTB1 by SUSD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →