SUPT7L

Across TCGA cell cohorts, SUPT7L protein abundance is significantly associated with the go_rna of many other GO terms, with 2,204 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SUPT7L-associated GO terms across cancer lineages are Regulation of plasminogen activation, Positive regulation of substrate adhesion-dependent cell spreading, and Fusion of virus membrane with host plasma membrane. Each is linked with SUPT7L in more than 4 cancer types. Because this analysis shows association rather than direction, both SUPT7L-to-partner and partner-to-SUPT7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasminogen activation grouped by SUPT7L-low versus SUPT7L-high in URINARY_TRACT.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT7L→partner) and Y-score (partner→SUPT7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of plasminogen activation →	+0.210	+1.167	<.001	<.001	3	5
URINARY_TRACT	Positive regulation of substrate adhesion-dependent cell spreading →	+0.095	+1.174	.002	.005	3	5
URINARY_TRACT	Fusion of virus membrane with host plasma membrane →	+0.277	+1.298	<.001	.002	3	5
URINARY_TRACT	Membrane fusion involved in viral entry into host cell →	+0.277	+1.298	<.001	.002	3	5
OESOPHAGUS	Protein folding →	+0.075	+0.704	.002	.006	3	4
LARGE_INTESTINE	Cellular response to hydrogen peroxide →	-0.051	-0.691	.005	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,204 associations by consensus.

Regulation of plasminogen activation by SUPT7L expression — URINARY_TRACT

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