SUPT6H

Across TCGA patient cohorts, SUPT6H protein abundance is significantly associated with the RNA expression of many other genes, with 19,366 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SUPT6H-associated genes across cancer lineages are TMEM199, E2F1, and MBTD1. Each is linked with SUPT6H in more than 9 cancer types. Because this analysis shows association rather than direction, both SUPT6H-to-partner and partner-to-SUPT6H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SUPT6H versus TMEM199 in LSCC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT6H→partner) and Y-score (partner→SUPT6H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM199 →	+0.589	+0.336	<.001	<.001	3	10
LSCC	E2F1 →	+0.896	+0.274	<.001	<.001	3	8
LSCC	MBTD1 →	+0.657	+0.322	<.001	<.001	3	8
LSCC	BRCA1 →	+1.117	+0.362	<.001	<.001	3	8
HNSC	DSN1 →	+0.762	+0.144	.003	.004	3	8
UCEC	SRSF2 →	+0.560	+0.203	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,366 associations by consensus.

SUPT6H vs TMEM199 — LSCC

Explore this scatter interactively →