Across TCGA patient cohorts, SUPT5H mutation is significantly associated with the RNA expression of many other genes, with 3,689 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT5H-associated genes across cancer lineages are DTL, MMS22L, and SKA3. Each is linked with SUPT5H in more than 4 cancer types. Because this analysis shows association rather than direction, both SUPT5H-to-partner and partner-to-SUPT5H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT5H→partner) and Y-score (partner→SUPT5H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DTL →	+0.594	+2.816	.006	.001	3	5
SKCM	MMS22L →	+0.427	+2.173	.001	.009	3	4
UCEC	SKA3 →	+0.466	+1.781	.001	.001	3	4
SKCM	CKAP2L →	+0.611	+3.195	.007	.009	3	4
UCEC	ZWILCH →	+0.364	+1.732	.002	.002	3	4
COAD	RBBP8 →	+0.661	+3.229	.002	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,689 associations by consensus.

Exploration

SUPT5H survival (RNA) · tumor vs normal (RNA) · all SUPT5H data types