Across TCGA patient cohorts, SUPT20HL2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT20HL2-associated genes across cancer lineages are C-Raf, Cyclin-E2, and 14-3-3_beta. Each is linked with SUPT20HL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT20HL2-to-partner and partner-to-SUPT20HL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT20HL2→partner) and Y-score (partner→SUPT20HL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.133	+1.415	.005	.043	3	2
LUAD	Cyclin-E2 →	+0.184	+3.016	.012	.019	3	1
UCEC	14-3-3_beta →	-0.081	-3.143	.016	.018	3	1
UCEC	INPP4B →	-0.309	-2.807	.004	.002	3	1
UCEC	JNK_pT183_Y185 →	-0.126	-1.700	.025	.042	3	1
UCEC	JNK2 →	+0.170	+1.901	.010	.028	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

SUPT20HL2 survival (RNA) · tumor vs normal (RNA) · all SUPT20HL2 data types