SUPT20H

Across TCGA patient cohorts, SUPT20H mutation is significantly associated with the RNA expression of many other genes, with 1,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT20H-associated genes across cancer lineages are RNU6-618P, RN7SKP295, and RNU6-669P. Each is linked with SUPT20H in more than 2 cancer types. Because this analysis shows association rather than direction, both SUPT20H-to-partner and partner-to-SUPT20H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-618P grouped by SUPT20H-low versus SUPT20H-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT20H→partner) and Y-score (partner→SUPT20H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-618P →	+0.224	+2.297	.003	<.001	3	3
UCEC	RN7SKP295 →	+0.218	+2.242	<.001	.005	3	3
THCA	RNU6-669P →	+0.329	+7.962	<.001	.007	3	2
BLCA	TMOD4 →	+0.012	+5.311	<.001	.001	3	2
BRCA	MIR4494 →	+0.285	+4.760	.003	.007	3	2
SKCM	IFNA8 →	+0.024	+5.219	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,747 associations by consensus.

RNU6-618P by SUPT20H expression — UCEC

Explore this box plot interactively →