SUMF2

Across TCGA patient cohorts, SUMF2 mutation is significantly associated with the RNA expression of many other genes, with 1,897 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUMF2-associated genes across cancer lineages are PRAMEF34P, RNU6-1207P, and RNU6-258P. Each is linked with SUMF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUMF2-to-partner and partner-to-SUMF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF34P grouped by SUMF2-low versus SUMF2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMF2→partner) and Y-score (partner→SUMF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PRAMEF34P →	+0.024	+5.105	<.001	.008	3	3
COAD	RNU6-1207P →	+0.527	+3.452	<.001	.009	3	2
COAD	RNU6-258P →	+0.388	+4.721	<.001	.004	3	2
UCEC	RN7SL248P →	+0.059	+3.500	<.001	.002	3	2
STAD	MIR3119-2 →	+0.349	+5.026	<.001	.009	3	2
UCEC	IGHD1-1 →	+0.653	+3.635	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,897 associations by consensus.

PRAMEF34P by SUMF2 expression — STAD

Explore this box plot interactively →