SULT6B1

Across TCGA patient cohorts, SULT6B1 mutation is significantly associated with the RNA expression of many other genes, with 502 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT6B1-associated genes across cancer lineages are POLR3KP2, RNU6-1213P, and IGLVI-68. Each is linked with SULT6B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT6B1-to-partner and partner-to-SULT6B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POLR3KP2 grouped by SULT6B1-low versus SULT6B1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT6B1→partner) and Y-score (partner→SULT6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	POLR3KP2 →	+0.321	+5.003	<.001	.004	3	2
UCEC	RNU6-1213P →	+0.184	+3.462	<.001	.002	3	2
UCEC	IGLVI-68 →	+0.074	+2.945	<.001	.002	3	2
CESC	DEFB103A →	+0.068	+6.837	<.001	<.001	3	2
CESC	RNU1-17P →	+0.459	+5.103	<.001	.008	3	2
BRCA	DEFB105A →	+0.079	+7.731	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 502 associations by consensus.

POLR3KP2 by SULT6B1 expression — COAD

Explore this box plot interactively →