SULT2A1

Across TCGA patient cohorts, SULT2A1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT2A1-associated genes across cancer lineages are TFRC, TSC1, and ATM. Each is linked with SULT2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT2A1-to-partner and partner-to-SULT2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by SULT2A1-low versus SULT2A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT2A1→partner) and Y-score (partner→SULT2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.640	+2.999	.007	.035	3	2
UCEC	TSC1 →	-0.230	-2.000	.002	.032	3	2
UCEC	ATM →	-0.483	-3.000	.018	.036	3	2
UCEC	EGFR_pY1068 →	-0.270	-3.807	.017	<.001	3	1
UCEC	INPP4B →	-0.316	-2.999	.030	.035	3	1
UCEC	JNK2 →	+0.200	+2.000	.025	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

TFRC by SULT2A1 expression — UCEC

Explore this box plot interactively →