SULT2A1

Across TCGA cell cohorts, SULT2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 722 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible SULT2A1-associated GO terms across cancer lineages are Regulation of isotype switching to IgE isotypes, Positive regulation of isotype switching to IgE isotypes, and Lipid homeostasis. Each is linked with SULT2A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SULT2A1-to-partner and partner-to-SULT2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of isotype switching to IgE isotypes grouped by SULT2A1-low versus SULT2A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT2A1→partner) and Y-score (partner→SULT2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of isotype switching to IgE isotypes →	-1.047	-2.830	.001	.005	3	4
LIVER	Positive regulation of isotype switching to IgE isotypes →	-1.047	-2.830	.001	.005	3	4
LIVER	Lipid homeostasis →	+0.084	+3.136	<.001	.002	3	4
LIVER	Amino acid metabolic process →	+0.062	+2.129	.001	.002	3	4
LIVER	Sulfur compound metabolic process →	+0.068	+2.146	<.001	.002	3	4
LARGE_INTESTINE	Retinoid metabolic process →	+0.081	+1.086	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 722 associations by consensus.

Regulation of isotype switching to IgE isotypes by SULT2A1 expression — LIVER

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