SULT2A1

Across TCGA cell cohorts, SULT2A1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SULT2A1-associated genes across cancer lineages are ZCCHC13, SPESP1, and GRM1. Each is linked with SULT2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT2A1-to-partner and partner-to-SULT2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZCCHC13 grouped by SULT2A1-low versus SULT2A1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT2A1→partner) and Y-score (partner→SULT2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ZCCHC13 →	+0.033	+5.285	<.001	.003	3	1
LARGE_INTESTINE	SPESP1 →	+0.714	+3.643	.001	.005	3	1
LARGE_INTESTINE	GRM1 →	+0.045	+3.750	<.001	.007	2	1
LARGE_INTESTINE	RSC1A1 →	+1.016	+3.519	.001	.007	2	1
LARGE_INTESTINE	GAS2L2 →	+0.150	+3.807	<.001	.003	2	1
LARGE_INTESTINE	WDR87 →	+0.023	+3.353	<.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ZCCHC13 by SULT2A1 expression — STOMACH

Explore this box plot interactively →