SULT1E1

Across TCGA patient cohorts, SULT1E1 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1E1-associated genes across cancer lineages are Caspase-8, c-Jun_pS73, and 14-3-3_beta. Each is linked with SULT1E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1E1-to-partner and partner-to-SULT1E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-8 grouped by SULT1E1-low versus SULT1E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1E1→partner) and Y-score (partner→SULT1E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.243	-2.973	.007	<.001	3	2
UCEC	c-Jun_pS73 →	-0.119	-3.571	.037	.002	3	2
UCEC	14-3-3_beta →	-0.078	-3.295	.030	.009	3	1
UCEC	eIF4G →	+0.243	+2.321	.030	.033	3	1
UCEC	JNK_pT183_Y185 →	-0.157	-1.912	.009	.005	3	1
UCEC	JNK2 →	+0.165	+2.348	.021	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Caspase-8 by SULT1E1 expression — UCEC

Explore this box plot interactively →