SUGT1P3

Across TCGA patient cohorts, SUGT1P3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SUGT1P3-associated genes across cancer lineages are GAGE13, RNU6-144P, and RNU6-285P. Each is linked with SUGT1P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUGT1P3-to-partner and partner-to-SUGT1P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE13 grouped by SUGT1P3-low versus SUGT1P3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUGT1P3→partner) and Y-score (partner→SUGT1P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GAGE13 →	+0.281	+8.049	<.001	<.001	3	1
BRCA	RNU6-144P →	+0.519	+5.506	<.001	.005	3	1
BRCA	RNU6-285P →	+0.653	+5.259	<.001	.007	3	1
BRCA	OTX2P1 →	+0.133	+5.203	<.001	.007	3	1
BRCA	MRPL50P4 →	+0.134	+5.883	<.001	.003	3	1
BRCA	LINC01221 →	+0.121	+5.230	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

GAGE13 by SUGT1P3 expression — BRCA

Explore this box plot interactively →