SUGT1-DT

Across TCGA pan-cancer cohorts, SUGT1-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SUGT1-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SUGT1-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SUGT1-DT expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

KIRC, ACC, and UVM are the cancer types where SUGT1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.518	0.715	<.001	129	view →
ACC	OS	Median	All	0.768	0.970	<.001	112	view →
UVM	DFS	Quartile	III,IV	0.183	0.903	<.001	62	view →
BLCA	OS	Tertile	II,III,IV	0.783	0.650	.001	56	view →
PAAD	OS	Median	All	0.625	0.372	<.001	44	view →
ESCA	DFS	Tertile	III,IV	0.207	0.525	<.001	32	view →
LAML	DFS	Median	All	0.542	0.240	.004	30	view →
SKCM	DFS	Median	III,IV	0.130	0.429	.001	25	view →
LUAD	OS	Tertile	III,IV	0.776	0.454	.008	23	view →
THYM	OS	Median	II,III,IV	1.000	0.659	<.001	20	view →
LIHC	OS	Tertile	III,IV	0.204	0.579	.007	18	view →
PRAD	DFS	Tertile	All	0.851	0.946	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SUGT1-DT–KIRC (DFS)

Open the KIRC breakdown →