SUGP1

Across TCGA cell cohorts, SUGP1 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SUGP1-associated genes across cancer lineages are RFPL3, OR10G2, and FAM47C. Each is linked with SUGP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUGP1-to-partner and partner-to-SUGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFPL3 grouped by SUGP1-low versus SUGP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUGP1→partner) and Y-score (partner→SUGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RFPL3 →	+0.048	+4.339	<.001	.002	3	2
BLOOD_Leukemia	OR10G2 →	+1.249	+3.551	<.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	FAM47C →	+0.069	+4.736	<.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	OR2B3 →	+0.061	+4.736	<.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	PRR23C →	+0.006	+4.736	<.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	MTRNR2L6 →	+0.173	+5.357	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

RFPL3 by SUGP1 expression — BLOOD_Leukemia

Explore this box plot interactively →