SUCLG1

Across TCGA pan-cancer cohorts, SUCLG1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SUCLG1 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SUCLG1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SUCLG1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where SUCLG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.712	0.344	.005	24	view →
CCRCC	OS	Median	IV	1.000	0.451	.016	8	view →
HNSC	DFS	Median	III,IV	0.740	0.519	.021	3	view →
LSCC	DFS	Quartile	III,IV	0.532	1.000	.025	2	view →
GBM	DFS	Tertile	All	0.222	0.450	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SUCLG1–PDAC (DFS)

Open the PDAC breakdown →