STYXL1

Across TCGA cell cohorts, STYXL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,466 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible STYXL1-associated GO terms across cancer lineages are Negative regulation of stress granule assembly, Regulation of stress granule assembly, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with STYXL1 in more than 19 cancer types. Because this analysis shows association rather than direction, both STYXL1-to-partner and partner-to-STYXL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stress granule assembly grouped by STYXL1-low versus STYXL1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STYXL1→partner) and Y-score (partner→STYXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of stress granule assembly →	+0.159	+1.166	<.001	<.001	3	20
BREAST	Regulation of stress granule assembly →	+0.123	+0.819	.003	.005	3	15
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.093	+1.119	<.001	<.001	3	11
BONE	Cytosolic ribosome assembly →	+0.073	+0.876	.006	.006	3	9
URINARY_TRACT	Membrane assembly →	+0.104	+0.773	<.001	.002	3	9
SOFT_TISSUE	Response to topologically incorrect protein →	+0.057	+0.790	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,466 associations by consensus.

Negative regulation of stress granule assembly by STYXL1 expression — URINARY_TRACT

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