Across TCGA cell cohorts, STYX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,646 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible STYX-associated GO terms across cancer lineages are Vesicle tethering to Golgi, Monoubiquitinated protein deubiquitination, and Protein localization to condensed chromosome. Each is linked with STYX in more than 12 cancer types. Because this analysis shows association rather than direction, both STYX-to-partner and partner-to-STYX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STYX→partner) and Y-score (partner→STYX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Vesicle tethering to Golgi →	+0.129	+0.646	<.001	<.001	3	13
BREAST	Monoubiquitinated protein deubiquitination →	+0.139	+0.692	<.001	<.001	3	12
OESOPHAGUS	Protein localization to condensed chromosome →	+0.182	+0.537	<.001	.007	3	11
LIVER	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.068	+0.449	<.001	.001	2	12
SOFT_TISSUE	Regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.120	+0.615	<.001	.004	3	11
LARGE_INTESTINE	Vesicle coating →	+0.058	+0.651	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

Exploration

STYX survival (RNA) · tumor vs normal (RNA) · all STYX data types