STXBP5L

Across TCGA patient cohorts, STXBP5L protein abundance is significantly associated with the RNA expression of many other genes, with 3,271 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STXBP5L-associated genes across cancer lineages are KEL, LINC00972, and RNU1-54P. Each is linked with STXBP5L in more than 2 cancer types. Because this analysis shows association rather than direction, both STXBP5L-to-partner and partner-to-STXBP5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STXBP5L versus KEL in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP5L→partner) and Y-score (partner→STXBP5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KEL →	+0.945	+0.619	<.001	<.001	3	2
LSCC	LINC00972 →	+0.105	+1.086	.005	.001	3	2
UCEC	RNU1-54P →	+2.266	+0.845	.005	<.001	2	3
GBM	KCNT1 →	+0.739	+0.485	<.001	<.001	3	2
GBM	STXBP1 →	+1.128	+0.605	<.001	<.001	3	2
LUAD	PRELID3A →	-1.015	-0.853	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

STXBP5L vs KEL — GBM

Explore this scatter interactively →