STXBP5

Across TCGA patient cohorts, STXBP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,978 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STXBP5-associated proteins across cancer lineages are SFRP2, SNX9, and STXBP5_S1131. Each is linked with STXBP5 in more than 5 cancer types. Because this analysis shows association rather than direction, both STXBP5-to-partner and partner-to-STXBP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STXBP5 versus SFRP2 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP5→partner) and Y-score (partner→STXBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SFRP2 →	+1.429	+0.872	<.001	<.001	3	6
OV	SNX9 →	+0.412	+0.654	<.001	.001	3	5
BRCA	STXBP5_S1131 →	+0.771	+0.672	<.001	<.001	3	5
CCRCC	SULF1 →	+0.964	+0.414	<.001	<.001	3	5
CCRCC	NUMBL →	+0.462	+0.456	<.001	<.001	3	5
CCRCC	P3H3 →	+0.650	+0.440	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,978 associations by consensus.

STXBP5 vs SFRP2 — OV

Explore this scatter interactively →