STXBP5

Across TCGA cell cohorts, STXBP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,271 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STXBP5-associated GO terms across cancer lineages are Protein localization to lysosome, Vacuolar transport, and Establishment of protein localization to vacuole. Each is linked with STXBP5 in more than 13 cancer types. Because this analysis shows association rather than direction, both STXBP5-to-partner and partner-to-STXBP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to lysosome grouped by STXBP5-low versus STXBP5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP5→partner) and Y-score (partner→STXBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to lysosome →	+0.091	+1.116	.002	.006	3	14
BONE	Vacuolar transport →	+0.062	+1.073	.008	.006	3	14
BONE	Establishment of protein localization to vacuole →	+0.091	+1.258	<.001	<.001	3	14
BONE	Endocytic recycling →	+0.084	+1.355	<.001	<.001	3	14
BONE	Golgi vesicle transport →	+0.070	+1.240	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Protein targeting to vacuole →	+0.077	+1.235	.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,271 associations by consensus.

Protein localization to lysosome by STXBP5 expression — OESOPHAGUS

Explore this box plot interactively →